Publications
February 25, 2025
Flow virometry: recent advancements, best practices, and future frontiers
Fernandes, C., Persaud, A. T., Chaphekar, D., Burnie, J., Belanger, C., Tang, V. A., & Guzzo, C. (2025). Flow virometry: Recent advancements, best practices, and future frontiers. Journal of Virology, 99 (2), e0171724. https://doi.org/10.1128/jvi.01717-24
December 6, 2024
​Comparing methods to detect cellular proteins on the surface of HIV-1 virions
Chaphekar, D., Fernandes, C., Persaud, A. T., & Guzzo, C. (2025). Comparing methods to detect cellular proteins on the surface of HIV-1 virions. Journal of Virological Methods, 333, 115096. https://doi.org/10.1016/j.jviromet.2024.115096
June 9, 2024
Applying Flow Virometry to Study the HIV Envelope Glycoprotein and Differences Across HIV Model Systems
Burnie, J., Fernandes, C., Patel, A., Persaud, A. T., Chaphekar, D., Wei, D., Lee, T. K. H., Tang, V. A., Cicala, C., Arthos, J., & Guzzo, C. (2024). Applying flow virometry to study the HIV envelope glycoprotein and differences across HIV model systems. Viruses, 16(6), 935. https://doi.org/10.3390/v16060935
May 14, 2024
Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells
Persaud, A. T., Khela, J., Fernandes, C., Chaphekar, D., Burnie, J., Tang, V. A., Colpitts, C. C., & Guzzo, C. (2024). Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells. Journal of Virology, 98(5), e0036324. https://doi.org/10.1128/jvi.00363-24
December 27, 2023
Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay
Burnie, J., Fernandes, C., Chaphekar, D., Wei, D., Ahmed, S., Persaud, A. T., Khader, N., Cicala, C., Arthos, J., Tang, V. A., & Guzzo, C. (2023). Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay. Scientific Reports, 13(1), 23025. https://doi.org/10.1038/s41598-023-50365-0
May 21, 2022
P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells
​Burnie, J., Persaud, A. T., Thaya, L., Liu, Q., Miao, H., Grabinsky, S., Norouzi, V., Lusso, P., Tang, V. A., & Guzzo, C. (2022). P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells. Retrovirology, 19(1), 9. https://doi.org/10.1186/s12977-022-00593-5
February 10, 2022
A UV-LED module that is highly effective at inactivating human coronaviruses and HIV-1
Persaud, A. T., Burnie, J., Thaya, L., DSouza, L., Martin, S., & Guzzo, C. (2022). A UV-LED module that is highly effective at inactivating human coronaviruses and HIV-1. Virology Journal, 19(1), 29. https://doi.org/10.1186/s12985-022-01754-w
June 11, 2021
Human monocytes store and secrete preformed CCL5, independent of de novo protein synthesis
Persaud, A. T., Bennett, S. A., Thaya, L., Burnie, J., & Guzzo, C. (2022). Human monocytes store and secrete preformed CCL5, independent of de novo protein synthesis. Journal of Leukocyte Biology, 111(3), 573–583. https://doi.org/10.1002/JLB.3A0820-522RR
November 12, 2020
Flow Virometry Quantification of Host Proteins on the Surface of HIV-1 Pseudovirus Particles
Burnie, J., Tang, V. A., Welsh, J. A., Persaud, A. T., Thaya, L., Jones, J. C., & Guzzo, C. (2020). Flow virometry quantification of host proteins on the surface of HIV-1 pseudovirus particles. Viruses, 12(11), 1296. https://doi.org/10.3390/v12111296
May 29, 2019
Pleiotropic Roles of Cytokines in HIV-1 Pathogenesis and Control: A Literature Review
Hamidzada, H., & Guzzo, C. (2019). Pleiotropic Roles of Cytokines in HIV-1 Pathogenesis and Control: A Literature Review. Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal, 3 (5), 1-10. doi:10.26685/urncst.128
January 20, 2019
The Incorporation of Host Proteins into the External HIV-1 Envelope
Burnie, J., & Guzzo, C. (2019). The incorporation of host proteins into the external HIV-1 envelope. Viruses, 11(1), 85. https://doi.org/10.3390/v11010085
December 11, 2018
Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation
Guzzo, C., Zhang, P., Liu, Q., Kwon, A. L., Uddin, F., Wells, A. I., . . . Lusso, P. (2018). Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation. MBio,9(6). doi:10.1128/mbio.00955-18
December 11, 2018
Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing
Guzzo, C., Ichikawa, D., Park, C., Phillips, D., Liu, Q., Zhang, P., Kwon, A., Miao, H., Lu, J., Rehm, C., Arthos, J., Cicala, C., Cohen, M. S., Fauci, A. S., Kehrl, J. H., & Lusso, P. (2017). Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing. Science Immunology, 2(11), eaam7341. https://doi.org/10.1126/sciimmunol.aam7341